Creatinine Clearance Calculator to Estimate GFR ...

What is Creatinine Clearance?

Creatinine clearance (CrCl) estimates how well the kidneys filter waste from blood. Creatinine is a muscle waste product excreted entirely by the kidneys. Reduced CrCl indicates impaired kidney function and requires drug dose adjustment to prevent accumulation of renally-cleared medications.

🫘 Creatinine Clearance Calculator

Use our free calculator for instant, accurate results.

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📐 Formula

CrCl = [(140−Age) × Weight × (0.85 if female)] / (72 × Serum Creatinine)

Cockcroft-Gault equation. Age in years, Weight in kg, Serum Creatinine in mg/dL (or μmol/L ÷ 88.4). Result in mL/min.

📝 Worked Example

Female, 65 years, 60 kg, creatinine = 1.2 mg/dL:
CrCl = [(140−65) × 60 × 0.85] / (72 × 1.2)
= [75 × 60 × 0.85] / 86.4 = 3825/86.4 = 44.3 mL/min
→ Stage 3a Chronic Kidney Disease

📝 How to Use the Calculator

Enter Patient DataAge, gender, weight, and serum creatinine level.

Select FormulaCockcroft-Gault (practical) or CKD-EPI (more accurate for eGFR).

Calculate CrCl/eGFRView result in mL/min or mL/min/1.73m².

CKD StageSee corresponding CKD stage (1–5) and interpretation.

❓ FAQ

What is eGFR vs CrCl?

eGFR (estimated GFR) is normalized for body surface area (mL/min/1.73 m²) and is the clinical standard. CrCl from Cockcroft-Gault is used for drug dosing.

What creatinine clearance is dangerous?

CrCl < 15 mL/min indicates kidney failure (Stage 5 CKD). CrCl < 30 mL/min requires significant dose reductions for renally-cleared drugs.

What is Creatinine Clearance?